Mild cognitive impairment: clinical characterization and outcome

RC Petersen, GE Smith, SC Waring, RJ Ivnik… - Archives of …, 1999 - jamanetwork.com
Background Subjects with a mild cognitive impairment (MCI) have a memory impairment
beyond that expected for age and education yet are not demented. These subjects are
becoming the focus of many prediction studies and early intervention trials. Objective To
characterize clinically subjects with MCI cross-sectionally and longitudinally. Design A
prospective, longitudinal inception cohort. Setting General community clinic. Participants A
sample of 76 consecutively evaluated subjects with MCI were compared with 234 healthy …