[HTML][HTML] Induction of tolerance to factor VIII by transient co‐administration with rapamycin
See also Miao CH. Tilt balance towards regulation: evolving new strategy for treatment of
hemophilia inhibitors. This issue, pp 1521–3. DOI: 10.1111/j. 1538‐7836.2011. 04351. x.
Summary Background: Formation of inhibitory antibodies is a frequent and serious
complication of factor (F) VIII replacement therapy for the X‐linked bleeding disorder
hemophilia A. Similarly, hemophilia A mice develop high‐titer inhibitors to recombinant
human FVIII after a few intravenous injections. Objective: Using the murine model, the study …
hemophilia inhibitors. This issue, pp 1521–3. DOI: 10.1111/j. 1538‐7836.2011. 04351. x.
Summary Background: Formation of inhibitory antibodies is a frequent and serious
complication of factor (F) VIII replacement therapy for the X‐linked bleeding disorder
hemophilia A. Similarly, hemophilia A mice develop high‐titer inhibitors to recombinant
human FVIII after a few intravenous injections. Objective: Using the murine model, the study …