Age-related changes in slow wave sleep and REM sleep and relationship with growth hormone and cortisol levels in healthy men

E Van Cauter, R Leproult, L Plat - Jama, 2000 - jamanetwork.com
ContextIn young adults, sleep affects the regulation of growth hormone (GH) and cortisol.
The relationship between decreased sleep quality in older adults and age-related changes
in the regulation of GH and cortisol is unknown. ObjectiveTo determine the chronology of
age-related changes in sleep duration and quality (sleep stages) in healthy men and
whether concomitant alterations occur in GH and cortisol levels. Design and SettingData
combined from a series of studies conducted between 1985 and 1999 at 4 laboratories …