[HTML][HTML] Is the cholesteryl ester transfer protein proatherogenic or antiatherogenic in humans?

M Cuchel, DJ Rader - Journal of the American College of Cardiology, 2007 - jacc.org
M Cuchel, DJ Rader
Journal of the American College of Cardiology, 2007jacc.org
The strong inverse association of plasma levels of highdensity lipoprotein cholesterol (HDL-
C) with coronary heart disease (CHD) has long tantalized the preventive cardiovascular
medicine community with the prospect of new therapies that raise levels of HDL-C and thus
reduce the risk of CHD. The finding that markedly elevated HDL-C levels are caused by
genetic deficiency of the cholesteryl ester transfer protein (CETP) and, subsequently,
The strong inverse association of plasma levels of highdensity lipoprotein cholesterol (HDL-C) with coronary heart disease (CHD) has long tantalized the preventive cardiovascular medicine community with the prospect of new therapies that raise levels of HDL-C and thus reduce the risk of CHD. The finding that markedly elevated HDL-C levels are caused by genetic deficiency of the cholesteryl ester transfer protein (CETP) and, subsequently,
jacc.org