Autophagy enables cells to degrade and recycle cytoplasmic materials both as a
housekeeping mechanism and in response to extracellular stress such as nutrient
deprivation. Recent studies indicate that autophagy also functions as a protective
mechanism in response to several cancer therapy agents, making it a prospective
therapeutic target. Few pharmacological inhibitors suitable for testing the therapeutic
potential of autophagy inhibition in vivo are known. An automated microscopy assay was …