Marijuana alters the human cerebellar clock

DS O'Leary, RI Block, BM Turner, J Koeppel… - …, 2003 - journals.lww.com
The effects of marijuana on brain perfusion and internal timing were assessed using [15 O]
water PET in occasional and chronic users. Twelve volunteers who smoked marijuana
recreationally about once weekly, and 12 volunteers who smoked daily for a number of
years performed a self-paced counting task during PET imaging, before and after smoking
marijuana and placebo cigarettes. Smoking marijuana increased rCBF in the ventral
forebrain and cerebellar cortex in both groups, but resulted in significantly less frontal lobe …