A Pilot Study on the Influence of a Corticotropin (4-9) Analogue on Vinca Alkaloid—Induced Neuropathy
B Van Kooten, HAM van Diemen… - Archives of …, 1992 - jamanetwork.com
• In a randomized, double-blind, placebo-controlled pilot study, we examined the effect of
Org 2766—a corticotropin (4-9) analogue—on neurotoxicity in 28 patients with lymphoma
who were treated with combination chemotherapy containingVincaalkaloids (vincristine and
vinblastine). The patients received a total dose of 12 mg of vincristine in the case of non-
Hodgkin's lymphoma and a total dose of 16 mg of vincristine in the case of Hodgkin's
disease. Moreover, the patients with Hodgkin's disease received a mean total dose of 84 mg …
Org 2766—a corticotropin (4-9) analogue—on neurotoxicity in 28 patients with lymphoma
who were treated with combination chemotherapy containingVincaalkaloids (vincristine and
vinblastine). The patients received a total dose of 12 mg of vincristine in the case of non-
Hodgkin's lymphoma and a total dose of 16 mg of vincristine in the case of Hodgkin's
disease. Moreover, the patients with Hodgkin's disease received a mean total dose of 84 mg …
