[HTML][HTML] Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family
L Gao, MA Cueto, F Asselbergs, P Atadja - Journal of Biological Chemistry, 2002 - ASBMB
We have cloned and characterized a human cDNA that belongs to the histone deacetylase
family, which we designate as HDAC11. The predicted HDAC11 amino acid sequence
reveals an open reading frame of 347 residues with a corresponding molecular mass of 39
kDa. Sequence analyses of the putative HDAC11 protein indicate that it contains conserved
residues in the catalytic core regions shared by both class I and II mammalian HDAC
enzymes. Putative orthologues of HDAC11 exist in primate, mouse, Drosophila, and plant …
family, which we designate as HDAC11. The predicted HDAC11 amino acid sequence
reveals an open reading frame of 347 residues with a corresponding molecular mass of 39
kDa. Sequence analyses of the putative HDAC11 protein indicate that it contains conserved
residues in the catalytic core regions shared by both class I and II mammalian HDAC
enzymes. Putative orthologues of HDAC11 exist in primate, mouse, Drosophila, and plant …