[PDF][PDF] Breaching the boundaries that safeguard against repression
Breaching the Boundaries that Safeguard against Repression Page 1 Molecular Cell Previews
Breaching the Boundaries that Safeguard against Repression Vijay K. Tiwari1 and Stephen B.
Baylin2,* 1Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland
2Cancer Biology Division, The Sidney Kimmel Comprehensive Cancer Center, The Johns
Hopkins University Medical Institutions, Baltimore, MD 21231, USA *Correspondence:
sbaylin1@jhmi.edu DOI 10.1016/j.molcel.2009.05.007 In a recent issue of Molecular Cell …
Breaching the Boundaries that Safeguard against Repression Vijay K. Tiwari1 and Stephen B.
Baylin2,* 1Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland
2Cancer Biology Division, The Sidney Kimmel Comprehensive Cancer Center, The Johns
Hopkins University Medical Institutions, Baltimore, MD 21231, USA *Correspondence:
sbaylin1@jhmi.edu DOI 10.1016/j.molcel.2009.05.007 In a recent issue of Molecular Cell …
In a recent issue of Molecular Cell, Witcher and Emerson (2009) demonstrate that CTCF loss of function, via defective steps in poly (ADP-ribosyl)ation, may predispose key genes in cancer cells to addition of abnormal promoter DNA methylation and silencing.
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