[CITATION][C] Hunger in humans induced by MK-329, a specific peripheral-type cholecystokinin receptor antagonist
OM Wolkowitz, B Gertz, H Weingartner, L Beccaria… - Biological …, 1990 - Elsevier
Since cholecystokinin (CCK) was discovered in 1928 (Ivy and Oldberg 1928) numerous
stud.~ es have sought to determine its physiological function in animals and in humans.
These investigations have been complicated by the subsequent discovery of different types
of CCK receptors, subclassified as the peripheral (ty~ A) and central (type B) CCK receptors
(Moran et al. 1986; Dourish and Hill 1987). Although located primarily in the digestive
system, peripheral-type receptors are also found in the centrai aervous system, in,~ species …
stud.~ es have sought to determine its physiological function in animals and in humans.
These investigations have been complicated by the subsequent discovery of different types
of CCK receptors, subclassified as the peripheral (ty~ A) and central (type B) CCK receptors
(Moran et al. 1986; Dourish and Hill 1987). Although located primarily in the digestive
system, peripheral-type receptors are also found in the centrai aervous system, in,~ species …
