Expression of inducible nitric oxide synthase, interleukin-1 and caspase-1 in HIV-1 encephalitis
ML Zhao, MO Kim, S Morgello, SC Lee - Journal of neuroimmunology, 2001 - Elsevier
Inflammatory cytokines and enzymes such as IL-1 and inducible nitric oxide synthase (iNOS)
may play an important role in the pathogenesis of AIDS dementia, a condition associated
with infection of the CNS cells by the HIV-1. In this report, we investigated the expression of
iNOS, IL-1, and caspase-1 (interleukin-1 converting enzyme) in HIV-1 encephalitis (HIVE) by
immunocytochemistry and analyzed their expression with respect to HIV-1 infection and glial
activation. In HIVE, all three molecules were expressed at high levels in areas of HIV-1 …
may play an important role in the pathogenesis of AIDS dementia, a condition associated
with infection of the CNS cells by the HIV-1. In this report, we investigated the expression of
iNOS, IL-1, and caspase-1 (interleukin-1 converting enzyme) in HIV-1 encephalitis (HIVE) by
immunocytochemistry and analyzed their expression with respect to HIV-1 infection and glial
activation. In HIVE, all three molecules were expressed at high levels in areas of HIV-1 …
