Expression of angiogenic factors, basic fibroblast growth factor and vascular endothelial growth factor, in human biliary tract carcinoma cell lines
S Ogasawara, H Yano, K Higaki, A Takayama… - Hepatology …, 2001 - Elsevier
In order to clarify angiogenic mechanism in biliary tract carcinoma, expressions and
functions of basic fibroblast growth factor (bFGF) and its receptors (FGFR-1–4), and vascular
endothelial growth factor (VEGF) and its receptors were investigated by using human biliary
tract carcinoma cell lines (KMC-1, KMC-2, KMBC and KMG-C). Expression of bFGF was
confirmed in KMC-1 and KMC-2, and that of FGFR-1–4 in all the cell lines except no FGFR-2
in KMC-2. Expression of VEGF was detected in all the cell lines, whereas the cell lines did …
functions of basic fibroblast growth factor (bFGF) and its receptors (FGFR-1–4), and vascular
endothelial growth factor (VEGF) and its receptors were investigated by using human biliary
tract carcinoma cell lines (KMC-1, KMC-2, KMBC and KMG-C). Expression of bFGF was
confirmed in KMC-1 and KMC-2, and that of FGFR-1–4 in all the cell lines except no FGFR-2
in KMC-2. Expression of VEGF was detected in all the cell lines, whereas the cell lines did …
