Microparticles: Modulators and biomarkers of liver disease
M Kornek, D Schuppan - Journal of hepatology, 2012 - journal-of-hepatology.eu
Microparticles (MP) have gained increasing attention as biomarkers for various diseases.
First described as platelet dust, MP were regarded as unspecific debris [1]. However, it has
become apparent that cell derived MP or ectosomes represent a novel route of horizontal
communication between cells. MP are between 100–1000 nm in size and generated
through cell membrane shedding (ectocytosis), a process that can be triggered by the
activation of the complement C5b-9 complex, as shown for platelet derived MP, or by …
First described as platelet dust, MP were regarded as unspecific debris [1]. However, it has
become apparent that cell derived MP or ectosomes represent a novel route of horizontal
communication between cells. MP are between 100–1000 nm in size and generated
through cell membrane shedding (ectocytosis), a process that can be triggered by the
activation of the complement C5b-9 complex, as shown for platelet derived MP, or by …
