Intra-arterial chemotherapy for the management of retinoblastoma: four-year experience

YP Gobin, IJ Dunkel, BP Marr, SE Brodie… - Archives of …, 2011 - jamanetwork.com
Objective: To determine whether intra-arterial chemotherapy is safe and effective in
advanced intraocular retinoblastoma. Retinoblastoma often presents with advanced
intraocular disease and, despite conventional treatment with intravenous chemotherapy and
external beam radiation therapy, may still require enucleation. Design: Single-arm,
prospective registry from May 30, 2006, to May 30, 2010, at an ophthalmic oncology referral
center with ambulatory care. A total of 95 eyes of 78 patients with unilateral or bilateral …