Microglia-specific localisation of a novel calcium binding protein, Iba1
D Ito, Y Imai, K Ohsawa, K Nakajima, Y Fukuuchi… - Molecular brain …, 1998 - Elsevier
Recently it has been shown that mRNA of Iba1 (ionized calcium binding adaptor molecule
1), which was a novel calcium binding protein cDNA-cloned by our group, is specifically
expressed in microglia in cultures of rat brain cells [Imai et al. Biophys. Biochem. Res.
Commun., 224 (1996) 855–862]. In the present study, immunocytochemical and
immunohistochemical examinations demonstrated that Iba1 protein is expressed in
microglia alone both in cultured brain cells and in the brain, respectively. In a mixed cell …
1), which was a novel calcium binding protein cDNA-cloned by our group, is specifically
expressed in microglia in cultures of rat brain cells [Imai et al. Biophys. Biochem. Res.
Commun., 224 (1996) 855–862]. In the present study, immunocytochemical and
immunohistochemical examinations demonstrated that Iba1 protein is expressed in
microglia alone both in cultured brain cells and in the brain, respectively. In a mixed cell …
