Demographic and family studies support the existence of a genetic contribution to the
pathogenesis of IgA nephropathy, but results from genetic association studies of candidate
genes are inconsistent. To systematically survey common genetic variation in this disease,
we performed a genome-wide analysis in a cohort of patients with IgA nephropathy selected
from the UK Glomerulonephritis DNA Bank. We used two groups of controls: parents of
affected individuals and previously genotyped, unaffected, ancestry-matched individuals …