Effect of latanoprost on the expression of matrix metalloproteinases and tissue inhibitor of metalloproteinase 1 on the ocular surface
N Honda, T Miyai, R Nejima, K Miyata… - Archives of …, 2010 - jamanetwork.com
Objective To investigate the effect of topical latanoprost on the expression of matrix
metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase 1 (TIMP-1) on the
ocular surface. Methods Tears were collected from 39 patients with glaucoma who used
latanoprost, 0.005%, eyedrops (Xalatan) and 28 healthy volunteers. The MMP-9
concentration was measured. Conjunctival epithelial cells were collected from 10 eyes of 10
patients before and 1 to 3 months after starting to take topical latanoprost, 0.005%, and MMP …
metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase 1 (TIMP-1) on the
ocular surface. Methods Tears were collected from 39 patients with glaucoma who used
latanoprost, 0.005%, eyedrops (Xalatan) and 28 healthy volunteers. The MMP-9
concentration was measured. Conjunctival epithelial cells were collected from 10 eyes of 10
patients before and 1 to 3 months after starting to take topical latanoprost, 0.005%, and MMP …