Monoclonal antibodies against ICAM-1 (CD54) and LFA-1 (CD11a/CD18) inhibit experimental autoimmune uveitis

SM Whitcup, LR DeBarge, RR Caspi, R Harning… - Clinical immunology and …, 1993 - Elsevier
Cell adhesion molecules are surface proteins important for cell migration and adhesion and
are strongly expressed in eyes with inflammation. We studied the expression of two cell
adhesion molecules: intercellular adhesion molecule-1 (ICAM-1, CD54) and lymphocyte
function-associated antigen-1 (LFA-1, CD11a/CD18) in mice with experimental autoimmune
uveitis. B10. A mice were immunized with interphotoreceptor retinoid-binding protein and
eyes were serially examined for expression of cell adhesion molecules using …