Mitochondrial function and redox control in the aging eye: role of MsrA and other repair systems in cataract and macular degenerations

LA Brennan, M Kantorow - Experimental Eye Research, 2009 - Elsevier
Oxidative stress occurs when the level of prooxidants exceeds the level of antioxidants in
cells resulting in oxidation of cellular components and consequent loss of cellular function.
Oxidative stress is implicated in wide range of age-related disorders including Alzheimer's
disease, Parkinson's disease amyotrophic lateral sclerosis (ALS), Huntington's disease and
the aging process itself. In the anterior segment of the eye, oxidative stress has been linked
to lens cataract and glaucoma while in the posterior segment of the eye oxidative stress has …