Angiotensin II type 1 receptor expression on human leukocyte subsets: a flow cytometric and RT-PCR study
E Rasini, M Cosentino, F Marino, M Legnaro… - Regulatory peptides, 2006 - Elsevier
The renin–angiotensin system plays a key role in the regulation of cardiovascular functions
and in particular angiotensin II type 1 receptor (AT1R)-operated pathways are involved in
the modulation of inflammation in the vascular wall. In the present study we assessed the
pattern of expression of AT1Rs on different human circulating leukocyte subsets. Venous
blood was obtained from healthy male subjects. Leukocyte subsets were purified by
immunomagnetic cell sorting or identified in whole blood using multiparametric cytometric …
and in particular angiotensin II type 1 receptor (AT1R)-operated pathways are involved in
the modulation of inflammation in the vascular wall. In the present study we assessed the
pattern of expression of AT1Rs on different human circulating leukocyte subsets. Venous
blood was obtained from healthy male subjects. Leukocyte subsets were purified by
immunomagnetic cell sorting or identified in whole blood using multiparametric cytometric …