Stimulation of an exocytotic event, the hamster sperm acrosome reaction, by cis‐unsaturated fatty acids

S Meizel, KO Turner - FEBS letters, 1983 - Wiley Online Library
S Meizel, KO Turner
FEBS letters, 1983Wiley Online Library
This cis‐unsaturated fatty acids oleic, arachidonic and cis‐vaccenic stimulated the hamster
sperm acrosome reaction in vitro (an exocytotic event which occurs in the sperm head and
which is essential for fertilization). The trans‐isomers of oleic and vaccenic acids did not
stimulate the acrosome reaction, nor did the cis‐unsaturated fatty acids petroselenic and
docosahexaenoic or the saturated fatty acids lauric, myristic or stearic. This is the first report
of a stimulatory effect of cis‐unsaturated fatty acids on an exocytic event in an intact viable …
This cis‐unsaturated fatty acids oleic, arachidonic and cis‐vaccenic stimulated the hamster sperm acrosome reaction in vitro (an exocytotic event which occurs in the sperm head and which is essential for fertilization). The trans‐isomers of oleic and vaccenic acids did not stimulate the acrosome reaction, nor did the cis‐unsaturated fatty acids petroselenic and docosahexaenoic or the saturated fatty acids lauric, myristic or stearic. This is the first report of a stimulatory effect of cis‐unsaturated fatty acids on an exocytic event in an intact viable cell.
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