Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trial
SJ Robins, D Collins, JT Wittes, V Papademetriou… - Jama, 2001 - jamanetwork.com
ContextA low plasma level of high-density lipoprotein cholesterol (HDL-C) is a major risk
factor for coronary heart disease (CHD). A secondary prevention study, the Veterans Affairs
High-Density Lipoprotein Intervention Trial (VA-HIT), demonstrated that CHD events were
significantly reduced during a median follow-up of 5.1 years by treating patients with the
fibric acid derivative gemfibrozil when the predominant lipid abnormality was low HDL-C.
ObjectiveTo determine if the reduction in major CHD events with gemfibrozil in VA-HIT could …
factor for coronary heart disease (CHD). A secondary prevention study, the Veterans Affairs
High-Density Lipoprotein Intervention Trial (VA-HIT), demonstrated that CHD events were
significantly reduced during a median follow-up of 5.1 years by treating patients with the
fibric acid derivative gemfibrozil when the predominant lipid abnormality was low HDL-C.
ObjectiveTo determine if the reduction in major CHD events with gemfibrozil in VA-HIT could …
