Oval cells—hepatocytes relationships in Dipin-induced hepatocarcinogenesis in mice
VM Factor, SA Radaeva - Experimental and Toxicologic Pathology, 1993 - Elsevier
During Dipin-induced hepatocarcinogenesis in mice there is powerful and prolonged
proliferation of oval cells which are arranged in duct-like structures. Ultrastructure and
differentiation pathways of oval cells depend on their location in the liver lobule. The major
part of oval cells is represented by duct lining cells morphologically similar to biliary
epithelial cells. They form the system of branching anastomozing ducts and expand into the
parenchyma from portal to central veins. Later these ducts disintegrate. In the periportal …
proliferation of oval cells which are arranged in duct-like structures. Ultrastructure and
differentiation pathways of oval cells depend on their location in the liver lobule. The major
part of oval cells is represented by duct lining cells morphologically similar to biliary
epithelial cells. They form the system of branching anastomozing ducts and expand into the
parenchyma from portal to central veins. Later these ducts disintegrate. In the periportal …
