The biologic actions of the cardiac peptide hormone atrial natriuretic peptide (ANP) of
vasorelaxation, diuresis and natriuresis, suppression of aldosterone, vasopressin release,
and thirst are the opposite of those of the renin angiotensin system. This close relationship is
further strengthened by the complementary localization of their receptors in the brain,
adrenal gland, vasculature, and kidney. In many physiologic situations including postural
changes, volume expansion, water immersion, high altitude, and lower body negative …