• We report fatal reticular dysgenesis in a premature infant presenting with severely
decreased blood and bone marrow granulocytes and lymphocytes, an absent thymic
shadow by x-ray film, and generalized lymphoid hypoplasia. Immunologic and electron
microscopic evaluation of his white blood cells demonstrated that, despite extremely low cell
numbers, cells from all stages of both granulocytic and lymphocytic development were
present. Immature bone marrow cells of both myeloid and lymphoid lineages were found in …