[HTML][HTML] Regulation by adrenocorticotropic hormone of the in vivo expression of scavenger receptor class B type I (SR-BI), a high density lipoprotein receptor, in …
A Rigotti, ER Edelman, P Seifert, SN Iqbal… - Journal of Biological …, 1996 - ASBMB
The class B, type I scavenger receptor, SR-BI, binds high density lipoprotein (HDL) and can
mediate selective uptake of HDL cholesteryl esters by cultured cells. The high levels of
expression of SR-BI in steroidogenic tissues and the importance of selective uptake from
HDL as a source of cholesterol for steroidogenesis raised the possibility that SR-BI may
participate in cholesterol delivery to steroidogenic tissues in vivo. We have used
immunoblotting and immunohistochemical methods to show that SR-BI is specifically …
mediate selective uptake of HDL cholesteryl esters by cultured cells. The high levels of
expression of SR-BI in steroidogenic tissues and the importance of selective uptake from
HDL as a source of cholesterol for steroidogenesis raised the possibility that SR-BI may
participate in cholesterol delivery to steroidogenic tissues in vivo. We have used
immunoblotting and immunohistochemical methods to show that SR-BI is specifically …
