Increase of deoxycholate in supersaturated bile of patients with cholesterol gallstone disease and its correlation with de novo syntheses of cholesterol and bile acids …
J Shoda, BF He, N Tanaka, Y Matsuzaki, T Osuga… - Hepatology, 1995 - Elsevier
A total of 100 nonobese and normolipidemic subjects (29 control subjects, 49 patients with
cholesterol stones [CSs], and 22 patients with brown pigment stones) were studied to
elucidate the pathogenetic contributions of deoxycholate (DC) to supersaturated bile
formation with special reference to de novo syntheses of cholesterol and bile acids in the
liver. A higher proportion of DC was observed in gallbladder bile from patients with CSs
(CSs; 21.7±1.4%, mean±SEM, vs. control subjects; 10.2±0.9%). Cholesterol saturation in …
cholesterol stones [CSs], and 22 patients with brown pigment stones) were studied to
elucidate the pathogenetic contributions of deoxycholate (DC) to supersaturated bile
formation with special reference to de novo syntheses of cholesterol and bile acids in the
liver. A higher proportion of DC was observed in gallbladder bile from patients with CSs
(CSs; 21.7±1.4%, mean±SEM, vs. control subjects; 10.2±0.9%). Cholesterol saturation in …
