Current status of live attenuated influenza virus vaccine in the US
RB Belshe - Virus research, 2004 - Elsevier
The efficacy and effectiveness of cold adapted live attenuated (CAIV-T, FluMist®) intranasal
influenza vaccine is reviewed. CAIV-T consists of approximately 107 TCID50 per dose of
each influenza A/H1N1, influenza A/H3N2, and influenza B vaccine strain. The exact strains
are updated each year to antigenically match the antigens recommended by national health
authorities for inclusion in the vaccine. In one year in which the vaccine strain did not well
match the epidemic strain, the live attenuated vaccine induced a broad immune response …
influenza vaccine is reviewed. CAIV-T consists of approximately 107 TCID50 per dose of
each influenza A/H1N1, influenza A/H3N2, and influenza B vaccine strain. The exact strains
are updated each year to antigenically match the antigens recommended by national health
authorities for inclusion in the vaccine. In one year in which the vaccine strain did not well
match the epidemic strain, the live attenuated vaccine induced a broad immune response …