Disruption of posterior brain systems for reading in children with developmental dyslexia

BA Shaywitz, SE Shaywitz, KR Pugh, WE Mencl… - Biological …, 2002 - Elsevier
Background: Converging evidence indicates a functional disruption in the neural systems for
reading in adults with dyslexia. We examined brain activation patterns in dyslexic and
nonimpaired children during pseudoword and real-word reading tasks that required
phonologic analysis (ie, tapped the problems experienced by dyslexic children in sounding
out words). Methods: We used functional magnetic resonance imaging (fMRI) to study 144
right-handed children, 70 dyslexic readers, and 74 nonimpaired readers as they read …