Immunohistochemical localization of the cloned μ opioid receptor in the rat CNS

A Mansour, CA Fox, S Burke, H Akil… - Journal of chemical …, 1995 - Elsevier
Three opioid receptor types have recently been cloned that correspond to the
pharmacologically defined μ, δ and κ1 receptors. In situ hybridization studies suggest that
the opioid receptor mRNAs that encode these receptors have distinct distributions in the
central nervous system that correlate well with their known functions. In the present study
polyclonal antibodies were generated to the C terminal 63 amino acids of the cloned μ
receptor (335–398) to examine the distribution of the μ receptor-like protein with …