Recent advances in the molecular pharmacology of the α1-adrenergic receptors
RD Guarino, DM Perez, MT Piascik - Cellular signalling, 1996 - Elsevier
RD Guarino, DM Perez, MT Piascik
Cellular signalling, 1996•ElsevierThis review is intended to discuss recent developments in the molecular pharmacology of
the α1-adrenergic receptor (α1-AR) subtypes. After a brief historical development will focus
on the more contemporary issues having to do with this receptor family. Emphasis will be put
on recent data regarding the cloning, nomenclature, signalling mechanisms, and genomic
organization of the α1-AR subtypes. We will also highlight recent mutational studies that
identify key amino acid residues involved in ligand binding, as well as the role of the α1-AR …
the α1-adrenergic receptor (α1-AR) subtypes. After a brief historical development will focus
on the more contemporary issues having to do with this receptor family. Emphasis will be put
on recent data regarding the cloning, nomenclature, signalling mechanisms, and genomic
organization of the α1-AR subtypes. We will also highlight recent mutational studies that
identify key amino acid residues involved in ligand binding, as well as the role of the α1-AR …
This review is intended to discuss recent developments in the molecular pharmacology of the α1-adrenergic receptor (α1-AR) subtypes. After a brief historical development will focus on the more contemporary issues having to do with this receptor family. Emphasis will be put on recent data regarding the cloning, nomenclature, signalling mechanisms, and genomic organization of the α1-AR subtypes. We will also highlight recent mutational studies that identify key amino acid residues involved in ligand binding, as well as the role of the α1-AR subtypes in regulating physiologic processes.
Elsevier