Increased low-density lipoprotein levels after splenectomy: a role for the spleen in cholesterol metabolism in myeloproliferative disorders
M Aviram, JG Brook, I Tatarsky, Y Levy… - The American journal of the …, 1986 - Elsevier
Patients with myeloproliferative disorders demonstrate decreased plasma cholesterol and
apolipoprotein B concentrations, and this has been related to the presence of a large
spleen. Patients that underwent splenectomy in the past demonstrated normal plasma
cholesterol levels. Plasma high-density lipoprotein (HDL) cholesterol and apolipoprotein AI
were also reduced in these patients, but were normal after splenectomy. To study the
immediate effect of splenectomy on the plasma lipid pattern, three patients with …
apolipoprotein B concentrations, and this has been related to the presence of a large
spleen. Patients that underwent splenectomy in the past demonstrated normal plasma
cholesterol levels. Plasma high-density lipoprotein (HDL) cholesterol and apolipoprotein AI
were also reduced in these patients, but were normal after splenectomy. To study the
immediate effect of splenectomy on the plasma lipid pattern, three patients with …
